diff --git a/mopidy/frontends/mpd/server.py b/mopidy/frontends/mpd/server.py
index db13e516..39a0e682 100644
--- a/mopidy/frontends/mpd/server.py
+++ b/mopidy/frontends/mpd/server.py
@@ -24,6 +24,9 @@ class MpdServer(asyncore.dispatcher):
         try:
             if socket.has_ipv6:
                 self.create_socket(socket.AF_INET6, socket.SOCK_STREAM)
+                # Explicitly configure socket to work for both IPv4 and IPv6
+                self.socket.setsockopt(
+                    socket.IPPROTO_IPV6, socket.IPV6_V6ONLY, 0)
             else:
                 self.create_socket(socket.AF_INET, socket.SOCK_STREAM)
             self.set_reuse_addr()